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Cell-type-specific eQTLs underlie the genetic architecture of complex traits
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10577-6 Single-cell RNA-sequencing shows that cell-type-specific expression quantitative trait loci drive much of complex trait heritability, highlighting cell-type-specific gene regulation as key to linking genetic
Systems vaccinology and the architecture of human immunity
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10753-8 A review of the current state of the field of systems vaccinology discusses the challenges in translating insights into clinical and regulatory practice.
Entries open for The Brick in Architecture Awards 2026
Promotion: entries are now open for this year's edition of the Brick in Architecture Awards, which recognises the best brick buildings from the US and beyond.
Six months into the Iran war, a new Gulf security architecture is emerging
Gulf states are building overlapping partnerships that complement, rather than replace, the US security role.
Hot Chips 2026: Cerebras lays out the future of wafer-scale AI — Nexus system architecture triples rack-scale performance, CS-6 wafer to incorporate stacked DRA
Cerebras' SRAM-packed wafer-scale engines (WSEs) have carved out a niche in the AI model serving space for extremely low-latency, high-throughput inference, enabling services like OpenAI's ChatGPT-5.6 Sol Ultrafast tier.
Hot Chips 2026: Nvidia presents Groq 3 LPX architecture and unveils its first third-party inference benchmark — LP30-based rack already in production, company s
Groq's former chief architect stood on stage at Hot Chips 2026 and presented his former company's inference chip as Nvidia silicon.
IBM Unveils Next Generation Dual-Architecture Processor for IBM Z and LinuxONE
Article URL: https://newsroom.ibm.com/2026-08-24-ibm-unveils-next-generation-dual-architecture-processor-for-ibm-z-and-linuxone Comments URL: https://news.ycombinator.com/item?id=49455471 Points: 135 # Comments: 99
Qwen3.8-Flash-Next: A New Architecture, Towards Ultimate Cost-Efficiency
Article URL: https://qwen.ai/blog?id=qwen3.8-flash-next Comments URL: https://news.ycombinator.com/item?id=49448210 Points: 283 # Comments: 87
Agentic Context Management: Memory and Cost as Architecture Problems
Article URL: https://arxiv.org/abs/2607.21503 Comments URL: https://news.ycombinator.com/item?id=49443523 Points: 59 # Comments: 23
Colourful cultural artefact storehouse among projects from London School of Architecture
Dezeen School Shows: a proposal for a storehouse in Brent, UK, that keeps cultural artefacts is among the student projects from the London School of Architecture. Also featured is a project that proposes "river rights" as a framework for rethinking our relationship with the natur
Hot Chips 2026: IBM's first dual-ISA core natively executes ARM and z/Architecture in the same core; all cores run at 5.7 GHz base frequency — next-gen mainfram
This Tom's Hardware Premium article is free to read with a Tom's Hardware account; no payment necessary. We're offering free access from August 23 to 26 so you can read all of our reporting from Hot Chips. IBM's next-gen AI processor is the first time it has supported dual ISA ex
Scalpel3: A High-Performance Data Carving Architecture for Recovery of Fragmented Files
arXiv:2608.20363v1 Announce Type: new Abstract: File carving recovers files from raw storage media without relying on filesystem metadata, a key capability in digital forensics, data recovery, and digital exploration. Traditional tools such as Foremost, Scalpel v1/2, and PhotoRec
AIA announces longest "ongoing slump" for architecture revenues
The American Institute of Architecture has announced the longest ever slump in architecture revenues in the US measured by the ABI index, citing "macroeconomic uncertainty" associated with rising oil prices. Today, the July report of the AIA/Deltek Architecture Billings Index (AB
Opinion: The global health aid architecture is collapsing. The faith economy isn’t
“Washington has rediscovered faith as a delivery mechanism. The bigger opportunity is faith as a source of capital,” writes Dr. Alaa Murabit.
archdaily.com
VENTUROUS exhibition charts a decade of innovative design research and practice from RMIT PhD alumni in Architecture & Urban Design.
This Historic Royal Palace Is Now India’s Most Breathtaking Retreat
At The Oberoi Rajgarh Palace in Khajuraho, you’ll find dazzling historic architecture, superb food, and a window into the region’s cultural wonders, from tiger safaris to bawdily decorated temples.
archdaily.com
Raw & Warm was conceived as a residential laboratory for an art collector—a home where architecture, art, and daily life could coexist without competing for attention. Rather than concealing the original structure, the design preserves the exposed concrete ceiling and its irregul
archdaily.com
Concéntrico returned to Logroño for its 12th edition in June 2026, transforming the city into a working site for architecture . Since its founding in 2015, the festival has built an identity on resisting a distant, controlled exhibition of design by constructing full-scale instal
archdaily.com
The 2026 Oslo Architecture Triennale will take place from September 17 to October 1 at Sofienberg Church in Oslo , bringing together more than 30 international architecture projects around the question "What if Nature Comes First?" For its ninth edition, the Triennale will adopt
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The Bahrain Authority for Culture and Antiquities invites individuals and collaborative teams to submit proposals to represent the National Pavilion of Bahrain at the 20th International Architecture Exhibition of La Biennale di Venezia, taking place from 8 May to 21 November 2027
Es Devlin Builds a Temporary Society in FUTURA SEOUL
Summary '3rd Poem' marks Es Devlin’s first solo exhibition in Korea.The show spans more than 30 years of work across light, sound, drawing, architecture and moving image.Visitors are folded into the exhibition through participatory works that explore presence, memory and collecti
With multilateralism in decline, what's next for the world?
The global political architecture is shifting, partly as a result of the actions of US President Donald Trump. As nations search for a new world order, some may gain influence and power, while others have much to lose.
Nodecraft Studio arranges Bengaluru farmhouse around poured-earth walls
Architecture practice Nodecraft Studio has created a farmhouse on the outskirts of Bengaluru from a cluster of poured-earth walls and concrete volumes linked by verandahs.
archdaily.com
Our goal was to create a place for the local community with inspiring architecture and environmental awareness - energy-efficient, based on renewable resources, using low-emission, natural materials, and blending into the surrounding nature and local context. ]]>
archdaily.com
Located in the Teusaquillo neighborhood—a central area of the city characterized by its historic brick architecture and vibrant cultural dynamics—Boroló offers a contemporary reinterpretation of the traditional neighborhood architecture that once defined Bogotá's identity. ]]>
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A weekend house among the trees, conceiving the existing landscape as an essential part of the architecture. ]]>
archdaily.com
Amid the transformation of Uzbekistan's cities, ARC Architects develops an architecture that seeks to connect past and present .
archdaily.com
Before establishing itself as a recognized language, modern architecture took shape through progressive shifts in ideas, experimentations, and critical revisions that traversed different cultural and geographical contexts.
archdaily.com
A12 Apartment transforms a historic Roman apartment into a contemporary home by using color, geometry, and spatial continuity to establish a new relationship between the existing architecture and everyday life. ]]>
archdaily.com
The Orrios Exchange (Lonja) building reflects the traditional "Exchange–Town Hall" typology characteristic of Teruel's vernacular architecture.
Square-metre studio strapped to tree in "exaggerated response" to office rental prices
German architecture studio Opposite Office has created a one-square-metre treehouse to work from, fixed to a tree at the Bauhaus University campus in Weimar.
archdaily.com
Located in a traditional neighborhood of Porto Alegre, the Tomaz Building embraces the concept of architecture as a legacy, standing out for its abundant greenery.
archdaily.com
World Architecture Festival, in partnership with Make Architects and Sir John Soane's Museum, has opened entries for the ninth edition of The Architecture Drawing Prize, sponsored by Iris Ceramica Group.
archdaily.com
Architecture across Latin America this month reflects an ongoing negotiation between environmental challenges, cultural heritage, and changing approaches to public and professional life.
archdaily.com
This week's news focused on how architecture engages with what already exists and communicates beyond the building itself.
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The courtyard-school concept guides the project, treating the space itself as a third educator and play as an essential pillar of the architecture.
Pearce+ stacks reclaimed materials to create multi-species wildlife tower
Architecture studio Pearce+ has added a wildlife tower for bats, owls, kestrels, invertebrates and wetland species at Honeygar Farm in Somerset, UK.
archdaily.com
In modern architecture , the promenade architecturale stood out as an essential design strategy to realize the principles of functionality, aesthetics, and integration with the urban context.
archdaily.com
Architecture across Latin America this month reflects an ongoing negotiation between environmental challenges, cultural heritage, and changing approaches to public and professional life.
archdaily.com
SEED 2026 is a gathering for specialists, professionals, students, and those interested in exploring new relationships between territory, architecture, biomaterials, and regenerative systems.
Do Ho Suh Brings Over 500 Works to Seoul's MMCA
Summary National Museum of Modern and Contemporary Art in Seoul, Korea is hosting a major solo exhibition by Do Ho SuhThe show features a career-spanning collection, including several of his colorful "fabric architecture" installations among unseen early works and recent textile
KFA set to transform 1970s brutalist LA office into apartments
Architecture studio KFA plans to convert a 1970s brutalist office in Los Angeles into housing after its recent designation as a historic landmark, taking advantage of a recently adopted adaptive reuse ordinance.
Colar revives adobe structure to create pared-back home in Mexico
Architecture studio Colar has updated and extended a dilapidated adobe structure to create a single-storey home in Chiapas, Mexico.
archdaily.com
Casa dell'Architettura of Rome announces the second edition of CONTEMPORANEA Call for Proposal (October–December 2026), with the aim of supporting original research and reflections in the field of contemporary architecture.
Grass-topped Dutch office by Studio Massimo "adds habitat rather than taking it"
Local architecture practice Studio Massimo has completed a bio-based office in the Netherlands, using bark cladding and an expansive green roof to disguise its form within the surrounding woodland.
Google’s Gemini has a branding problem, and so does the rest of AI
Consumer AI apps need to stop making users learn their product architecture.
Big-name studios encouraging architects to use AI
The world's most prominent architecture studios are embracing AI for everything from coming up with designs to project analyses and reports, Dezeen research has found.
Construction begins on world's tallest jail in Manhattan
A skyscraper-sized jail designed by architecture studio HOK is undergoing site preparation in New York City's Chinatown as one of the four new borough-based structures designed to replace the city's notorious Rikers Island jail complex. The Manhattan Detention Facility will be lo
archdaily.com
The Glass House (Casa de Vidro) was conceived from a contemporary architecture of strong horizontal expression, where the lightness of the planes and the precision of the lines define a sophisticated and timeless aesthetic. The large cantilevered roof plane, a striking element of
archdaily.com
Esquina Nativa rethinks the relationship between commercial architecture, landscape, and public space in the contemporary city. Located on the corner of the former Cholul nursery in Mérida, the project stems from a fundamental decision: to preserve the existing vegetation and bui
Centre plans integrated command centres to step up border security
The ‘smart border’ architecture will integrate AI, sensors, surveillance systems and unified command-and-control centres, says official; focus on addressing threat from drones used for smuggling; pilot project to start soon from Pakistan border
Apple's new desktop computers are designed specifically for local AI development
The Mac mini and Mac Studio occupy two distinct points in Apple's lineup of desktops, but lately, they've had something in common: They're popular for local AI inference and software development thanks to the advantages of their unified memory architecture and the fast CPUs and G
archdaily.com
The site of Cabin Sande is defined by the vast horizon over the Atlantic Ocean, the dark and rough rocky landscape descending toward the sea, and the untouched natural vegetation in the rear part of the property. Our aim was to create an architecture that connects these distinct
Apple Unveils the New Mac Mini With M6 and M5 Pro Chips
Summary Apple announced an updated Mac mini featuring the all-new M6 and M5 Pro chips, marking the debut of the company's first 2nm silicon in a desktop form factorThe M6 configuration offers a 12-core CPU with a new super core architecture and a 12-core GPU with integrated Neura
Audi Unveils the Nuvolari, a 987 HP Mid-Engine Supercar Limited to Just 499 Units Globally
Summary Audi debuts the limited-edition Nuvolari supercar with a 987-horsepower plug-in hybrid V-8 powertrainThe mid-engine halo car shares its architecture with the Lamborghini Temerario but adds larger batteries and a tri-motor setup for increased outputProduction is restricted
archdaily.com
The Universidad Católica de Córdoba operates on a campus that, following the traditional format, originally assigned a building to each academic unit or field of study. In a contemporary world that demands interdisciplinary research and design dynamics, architecture must transcen
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The Abejas Sports and Recreation Center in Tijuana explores the role architecture can play in improving everyday life in underserved areas. Developed within a neighborhood shaped by rapid urban growth and limited access to quality public infrastructure, the project introduces a s
KTGY revamps interiors of Fairmont Hotel in Chicago
US architecture studio KTGY has revamped the interiors of the HOK-designed Fairmont Hotel off of Chicago's Millennium Park. KTGY's Interiors Studio was brought on to refresh the detailing and bring light into the dark spaces of the hotel, with a focus on the premium rooms and lou
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Obra Blanca is an essential experience for professionals in the architecture finishes and design products sector, including ceramics, bathroom furniture, faucets, lighting, and more. It offers a unique opportunity to scale projects and achieve new objectives by interacting and co
ZHA proposes interconnected forest neighbourhoods for Baku Expo City masterplan
Architecture studio ZHA has unveiled its masterplan for Baku Expo City in Azerbaijan, where overlapping stacked homes with green roofs will flank an extension to the city's exhibition centre. The 198-hectare-site in Baku will have residences ranging from one-bedroom flats to larg
Photos reveal world's tallest hotel in Dubai
Photographer Ahmad Alnaji has captured the Ciel Dubai Marina, a supertall skyscraper by architecture studio NORR that was recently completed as the tallest hotel in the world. Ciel Dubai Marina opened in November last year, rising 377 metres to beat the 356-metre-tall Gevora Hote
UUfie organises renovated Ontario chalet "like a hike"
Toronto architecture studio UUfie has expanded and renovated a 1970s chalet in Ontario to conform to its steep, wooded site with a net that serves as an internal barrier and a hammock. Set on 3 acres within the Niagara Escarpment, Belfountain House preserves the northern portion
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Casa Zimbro was born from the search for an architecture in continuity with the landscape, where the construction does not impose itself on its surroundings but rather integrates with them in a natural and sensitive way. Sited between the lake and the garden, the house is designe
Visualisation has become more than creating "a single visual output" says Chaos
Promotion: according to software company Chaos, AI-assisted tools, advances in rendering technologies, and shifting client expectations are transforming the architecture industry's visualisation workflows into a flexible communication tool. Chaos explained that utilising artifici
Architects are sitting on a data gold mine, and Anthropic and other frontier AI labs can’t get to it
Architecture may be one of AI ’s hardest pursuits. Unlike coding or writing, the data that could be used to train an architecture AI model is not widely available (or stealable ) online. Rather, it’s stored away in the servers and physical filing cabinets of individual architectu
My Favorite Airbnb: A Gorgeous Family Villa on a Special Stretch of the Algarve
A Belle Époque–style home where local influences and geometric architecture meet the picturesque Portuguese coastline.
Xiang Architects creates steel double-helix viewpoint for bird watching in China
Architecture studio Xiang Architects has unveiled a multi-stair observation tower within the Chenhu Wetland bird sanctuary near Wuhan City, China. Named the Chenhu Migratory Bird Observation Tower, the viewpoint rises 19.8 metres above the surrounding marshland that becomes home
Zara flagship store in Shanghai reflects "the future of physical retail"
AIM Architecture has designed Zara Huaihai Road, a flagship store for the Spanish fashion brand in Shanghai, with an amphitheatre-like brick podium that connects the building with the street. Located on Huaihai Road, a well-known commercial district in central Shanghai, the new f
What Trump’s crush on Kim means for the Indo-Pacific
As the U.S president cozies up to the North Korean dictator, America's allies in the region are building a new defense architecture.
Demountable timber library in Amsterdam is "a living room for the neighbourhood"
Stepped, pastel-pink seating spills out from inside the OBA Next Lab library and community space in Amsterdam, designed by Dutch architecture practices Matter Makers, AWR and BAZ Studio as a public living room. Completed for The Public Library of Amsterdam, or OBA, the 1,175-squa